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Crospovidone

(IP / BP / USP / NF / Ph.Eur)

Super Disintegrant

Crospovidone, also known as cross-linked Polyvinylpyrrolidone (PVP), is a white to creamy-white, odorless, and hygroscopic powder. It is an insoluble, synthetic polymer specifically designed for its exceptional disintegration capabilities within pharmaceutical and nutraceutical formulations.

Crospovidone

Crospovidone, also known as cross-linked Polyvinylpyrrolidone (PVP), is a white to creamy-white, odorless, and hygroscopic powder. It is an insoluble, synthetic polymer specifically designed for its exceptional disintegration capabilities within pharmaceutical and nutraceutical formulations.

Specifications

  • Moisture content: <10%
  • pH: 5.0 - 7.0 (as an aqueous suspension)
  • May include limits for heavy metals and residual solvents

Features

Possesses rapid swelling and wicking action upon contact with water.

Promotes fast and efficient disintegration of tablets and capsules, leading to enhanced drug dissolution.

Effective at low concentrations, minimizing excipient load.

Compatible with a broad range of active pharmaceutical ingredients (APIs).

Suitable for various manufacturing processes, including direct compression and wet granulation.

Applications

  • Pharmaceutical

    A leading superdisintegrant for tablets and capsules, optimizing drug release profiles.

  • Nutraceutical

    Used to improve the disintegration of dietary supplements in solid dosage forms.

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