PARCROS
Croscarmellose Sodium
(IP / BP / USP / NF / Ph.Eur)
Croscarmellose sodium is a chemically cross-linked form of sodium Carboxymethyl Cellulose, designed to function as a highly effective superdisintegrant within pharmaceutical and nutraceutical formulations. It appears as a white to off-white, odorless, and free-flowing powder. This excipient offers exceptional disintegration capabilities, promoting rapid tablet breakdown and subsequent dissolution of active ingredients.
Croscarmellose sodium is a chemically cross-linked form of sodium Carboxymethyl Cellulose, designed to function as a highly effective superdisintegrant within pharmaceutical and nutraceutical formulations. It appears as a white to off-white, odorless, and free-flowing powder. This excipient offers exceptional disintegration capabilities, promoting rapid tablet breakdown and subsequent dissolution of active ingredients.
Specifications
- Moisture content (loss on drying): Below 10%
- pH range: 5.0 - 7.0
- Degree of substitution: 0.60 - 0.85
Features
Exhibits rapid disintegration and enhanced drug release profiles.
Demonstrates superior swelling capacity, leading to faster dissolution rates compared to traditional disintegrants.
Offers excellent compatibility and stability with a broad range of active pharmaceutical ingredients (APIs).
Highly effective at low concentrations, minimizing excipient load.
Ideal for use in direct compression, wet granulation, and various tableting processes.
Applications
Pharmaceutical
Widely used as the primary disintegrant in a multitude of solid oral dosage forms, including tablets and capsules.
Nutraceutical
Enhances the disintegration and dissolution of dietary supplements formulated as tablets or capsules.
Food (Limited)
Potential applications may include thickening and stabilizing functions (subject to regional regulations).
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